There are times in life when the challenges we face feel insurmountable. Authors succumb to writer’s block. Athletes and artists hit a plateau. People of a certain age fall into a midlife crisis. These are all different ways of saying: I’m stuck. This week, in a favorite conversation from 2023, psychologist Adam Alter shares his research on why we all get stuck at various points in our lives, and how to break free. Then, psychologist George Bonanno answers your questions about trauma and resilience.In this episode, you'll learn:*Why the beginning and the end of a project is often more manageable than the midway point.*Techniques that can help you to get through the "plateau" phase of a project or goal. *How to break down daunting endeavors into smaller, more manageable pieces.*Why perfectionism is so destructive to creativity, and how we can avoid this mental trap.*Why it's difficult for us to see other people's "stuckness." *The relationship between being prolific and being successful. Hidden Brain is heading back out on the road in 2026! We're coming next to Philadelphia and New York City, with more tour dates across the country to be announced later this spring. More info and tickets at hiddenbrain.org/tour. Episode illustration by Getty Images for Unsplash+. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
There are times in life when the challenges we face feel insurmountable. Authors succumb to writer’s block. Athletes and artists hit a plateau. People of a certain age fall into a midlife crisis. These are all different ways of saying: I’m stuck. This week, in a favorite conversation from 2023, psychologist Adam Alter shares his research on why we all get stuck at various points in our lives, and how to break free. Then, psychologist George Bonanno answers your questions about trauma and resilience.In this episode, you'll learn:*Why the beginning and the end of a project is often more manageable than the midway point.*Techniques that can help you to get through the "plateau" phase of a project or goal. *How to break down daunting endeavors into smaller, more manageable pieces.*Why perfectionism is so destructive to creativity, and how we can avoid this mental trap.*Why it's difficult for us to see other people's "stuckness." *The relationship between being prolific and being successful. Hidden Brain is heading back out on the road in 2026! We're coming next to Philadelphia and New York City, with more tour dates across the country to be announced later this spring. More info and tickets at hiddenbrain.org/tour. Episode illustration by Getty Images for Unsplash+. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
When neuroscientist Madeline Lancaster was a brand new postdoc, she accidentally used an expired protein gel in a lab experiment and noticed something weird. The stem cells she was trying to grow in a dish were self-assembling. The result? Madeline was the first person ever to grow what she called a “cerebral organoid,” a tiny, 3D version of a human brain the size of a peppercorn.In about a decade, these mini human brain balls were everywhere. They were revealing bombshell secrets about how our brains develop in the womb, helping treat advanced cancer patients, being implanted into animals, even playing the video game Pong. But what are they? Are these brain balls capable of sensing, feeling, learning, being? Are they tiny, trapped humans? And if they were, how would we know?Special thanks to Lynn Levy, Jason Yamada-Hanff, David Fajgenbaum, Andrew Verstein, Anne Hamilton, Christopher Mason, Madeline Mason-Mariarty, the team at the Boston Museum of Science, and Howard Fine, Stefano Cirigliano, and the team at Weill-Cornell. EPISODE CREDITS: Reported by - Latif Nasserwith help from - Mona MadgavkarProduced by - Annie McEwen, Mona Madgavkar, and Pat Walterswith mixing help from - Jeremy BloomFact-checking by - Natalie Middleton and Rebecca Randand Edited by - Alex Neason and Pat WaltersEPISODE CITATIONS:Videos - “Growing Mini Brains to Discover What Makes Us Human,” Madeline Lancaster’s TEDxCERN Talk, Nov 2015 (https://zpr.io/6WP7xfA27auR)Brain cells playing Pong (https://zpr.io/pqgSqguJeAPK)Reuters report on CL1 computer launch in March 2025 (https://zpr.io/cdMf8Yjvayyd) Articles - Madeline Lancaster: The accidental organoid – mini-brains as models for human brain development (https://zpr.io/nnwFwUwnm2p6), MRC Laboratory of Molecular Biology What We Can Learn From Brain Organoids (https://zpr.io/frUfsg4pxKsb), by Carl Zimmer. NYT, November 6, 2025Ethical Issues Related to Brain Organoid Research (https://zpr.io/qyiATHEhdnSa), by Insoo Hyun et al, Brain Research, 2020 Brain organoids get cancer, too, opening a new frontier in personalized medicine (https://zpr.io/nqMCQ) STAT Profile of Howard Fine and his lab’s glioblastoma research at Weill Cornell Medical Center: By re-creating neural pathway in dish, Stanford Medicine research may speed pain treatment (https://zpr.io/UnegZeQZfqn2) Stanford Medicine profile of Sergiu Pasca’s research on pain in organoids A brief history of organoids (https://zpr.io/waSbUCSrL9va) by Corrò et al, American Journal of Physiology - Cell Physiology, Books - Carl Zimmer Life’s Edge: The Search for What it Means to be Alive (https://carlzimmer.com/books/lifes-edge/)Sign up for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Signup (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
We all want to stay sharp, and forestall the cognitive effects of aging. But do brain supplements actually work? Are they safe? And why doesn’t the F.D.A. even know what’s in them? (Part one of “The Freakonomics Radio Guide to Getting Better.”) SOURCES:Marty Makary, commissioner of the Food and Drug Administration.Peter Attia, physician, author, and host of The Peter Attia Drive.Pieter Cohen, associate professor of medicine at Harvard Medical School, physician at the Cambridge Health Alliance. RESOURCES:"Protein Powders and Shakes Contain High Levels of Lead," by Paris Martineau (Consumer Reports, 2025)."Accuracy of Labeling of Galantamine Generic Drugs and Dietary Supplements," by Pieter Cohen, Bram Jacobs, Koenraad Van Hoorde, and Céline Vanhee (JAMA, 2024).Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health, by Marty Makary (2024).Outlive: The Science and Art of Longevity, by Petter Attia (2023)."Revealing the hidden dangers of dietary supplements," by Jennifer Couzin-Frankel (Science, 2015). EXTRAS:"China Is Run by Engineers. America Is Run by Lawyers." by Freakonomics Radio (2025)."How to Fix the Hot Mess of U.S. Healthcare," by Freakonomics Radio (2021). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
First up on the podcast, scholars are on a quest to find Leonardo da Vinci’s DNA. With no direct descendants, the hunt involves sampling the famous polymath’s papers, paintings, and distant cousins. Contributing Correspondent Richard Stone talks with host Sarah Crespi about what researchers hope to learn from Leonardo’s genes and the new field of “arteomics.”
Next on the show, new evidence for poisoned arrows from 60,000 years ago complicates our picture of hunting during the Pleistocene. Sven Isaksson, a professor of archaeological science at Stockholm University, joins the podcast to discuss the discovery of poisonous residues on microliths—the tiny, worked stone points used on arrows and spearheads. These findings could push back the origins of this toxic technology by 50,000 years.
This week’s episode was produced with help from Podigy.
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Why do some people act bravely in a crisis, while others flee or freeze up? Today, we bring you the second part of our You 2.0 series on the mental obstacles that can block us when we're charting a new path. Behavioral scientist Ranjay Gulati argues that courage is a choice, and that we can strengthen the reflexes that will help us to be brave when it matters most. Once you've listened to this episode, be sure to check out our companion conversation about how you can help the people around you to become more brave. You can hear that episode with a free seven-day trial to Hidden Brain+. To sign up, go to support.hiddenbrain.org or apple.co/hiddenbrain. Your subscription helps to cover the research, writing, and audio production that go into every episode of Hidden Brain, and we appreciate your support!Episode illustration by Eva Wahyuni for Unsplash+ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
The World Health Organization conditionally recommended glucagon-like peptide-1 (GLP-1) therapies for obesity treatment in December 2025. Canada could soon become the first country in the world to offer a cheaper version of Ozempic and Wegovy to people with prescriptions.Our question: Would you take a drug to lose weight...or have you already?
American forces stormed Caracas and captured Venezuelan President Nicolás Maduro on Saturday. U.S. President Donald Trump said the United States is “going to run” Venezuela for the time being.Our question: What’s your reaction to the U.S. strike on Venezuela? What questions do you have?
In 1971, a red-headed, tree-loving astronaut named Stu ‘Smokey’ Roosa was asked to take something to the moon with him. Of all things, he chose to take a canister of 500 tree seeds. After orbiting the moon 34 times, the seeds made it back to Earth. NASA decided to plant the seeds all across the country and then… everyone forgot about them. Until one day, a third grader from Indiana stumbled on a tree with a strange plaque: "Moon Tree." This discovery set off a cascading search for all the trees that visited the moon across the United States. Science writer, and our very own factchecker, Natalie Middleton (https://www.nataliemiddleton.org/) tells us the tale.Read Lulu’s remembrance of Alice Wong for Transom.org: 13 questions I’ll never get to ask Alice Wong (https://transom.org/2025/13-questions-ill-never-get-to-ask-alice-wong/). Check out Natalie’s map to find your nearest moon tree on our show page (https://radiolab.org/podcast/the-travelers-how-moon-trees-hide-among-us)!Help us hunt for more moon trees. If you know of an undocumented moon tree, contact Natalie at nataliemiddleton.org. Check out Natalie’s essay on Moon Trees (https://orionmagazine.org/article/moon-tree/) and Space Zinnias (https://orionmagazine.org/article/astronaut-scott-kelly-flower-experiment-space/) in Orion Magazine (https://orionmagazine.org/).Visit NASA’s official Moon Tree Page (https://science.nasa.gov/resource/apollo-moon-trees/) for a list of all the Apollo 14 Moon Trees in the world. To learn more about Stu Roosa or to learn more about acquiring your own half Moon Tree, check out the Moon Tree Foundation (https://www.moontreefoundation.com/), spearheaded by Stu’s daughter, Rosemary Roosa. A reminder that Terrestrials also makes original music! You can find ‘Tangled in the Roots’ and all other music from the show here (https://www.wnycstudios.org/podcasts/radiolab-kids/just-the-songs).EPISODE CREDITS: Terrestrials was created by Lulu Miller with WNYC Studios. This episode was produced by Tanya Chawla and sound-designed by Joe Plourde. Our Executive Producer is Sarah Sandbach. Our team includes Alan Goffinski, Ana González and Mira Burt-Wintonick. Fact checking was by Diane Kelly. Special thanks to Sumanth Prabhaker from Orion magazine, retired NASA Scientist Dr. Dave Williams, Joan Goble, Tre Corely and NASA scientist Dr. Marie Henderson.Our advisors for this show were Ana Luz Porzecanski, Nicole Depalma, Liza Demby and Carly Ciarrocchi.Support for Terrestrials also comes from the Simons Foundation, the Arthur Vining Davis Foundations, and the John Templeton Foundation.Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
One Yale economist certainly thinks so. But even if he’s right, are economists any better? We find out, in this update of a 2022 episode. SOURCES:James Choi, professor of finance at the Yale School of Management.Morgan Housel, personal finance author and partner at the Collaborative Fund. RESOURCES:The Art of Spending Money: Simple Choices for a Richer Life, by Morgan Housel (2025).“Popular Personal Financial Advice versus the Professors,” by James J. Choi (Journal of Economic Perspectives, 2022).“Media Persuasion and Consumption: Evidence from the Dave Ramsey Show,” by Felix Chopra (SSRN, 2021).The Psychology of Money: Timeless Lessons on Wealth, Greed, and Happiness, by Morgan Housel (2020).“In Bogle Family, It’s Either Passive or Aggressive,” by Liam Pleven (Wall Street Journal, 2013). EXTRAS: “Harold Pollack on Why Managing Your Money Is as Easy as Taking Out the Garbage,” by People I (Mostly) Admire (2021).“People Aren’t Dumb. The World Is Hard,” by Freakonomics Radio (2018).“Everything You Always Wanted to Know About Money (But Were Afraid to Ask),” by Freakonomics Radio (2017).“The Stupidest Thing You Can Do With Your Money,” by Freakonomics Radio (2017). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
First up on the podcast, the best images of exoplanets right now are basically bright dots. We can’t see possible continents, potential oceans, or even varying colors. To improve our view, scientists are proposing a faraway fleet of telescopes that would use light bent by the Sun’s gravity to magnify a distant exoplanet. Staff Writer Daniel Clery joins host Sarah Crespi to discuss where to aim such a magnificent telescope and all the technological pieces needed to put it together.
Next on the show, expert voices columnist and Johns Hopkins University mathematician Emily Riehl discusses her recent essay on communication woes in the math community. The complex concepts, jargon, and the slow pace of understanding a proof all add up to siloed subdisciplines and potentially more errors in the literature. Alex Kontorovich, a professor in the math department at Rutgers University, also joins to discuss how proof assistant computer programs and machine learning could help get mathematicians all on the same page.
This week’s episode was produced with help from Podigy.
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Behavioral scientists have been exploring whether a psychological reset can lead to lasting change. In this update of a 2021 episode, we survey evidence from the London Underground, Major League Baseball, and New Year’s resolutions to look at accidental fresh starts, forced fresh starts, fresh starts that backfire — and the ones that succeed. SOURCES:Katy Milkman, professor at the Wharton School.Andy Byford, former commissioner of Transport for London.Ferdinand Rauch, economist at the University of St. Gallen.Hengchen Dai, professor at U.C.L.A.’s Anderson School of Management.Bob Tewksbury, former big-league pitcher. RESOURCES:“A Large-Scale Experiment on New Year’s Resolutions: Approach-Oriented Goals are More Successful than Avoidance-Oriented Goals,” by Martin Oscarsson, Per Carlbring, Gerhard Andersson, and Alexander Rozental (PLOS ONE, 2020).“A Double-Edged Sword: How and Why Resetting Performance Metrics Affects Motivation and Performance,” by Hengchen Dai (Organizational Behavior and Human Decision Processes, 2018).“The Benefits of Forced Experimentation: Striking Evidence from the London Underground Network,” by Shaun Larcom, Ferdinand Rauch, and Tim Willems (2017).“Framing the Future: The Risks of Pre-Commitment Nudges and Potential of Fresh Start Messaging,” by John Beshears, Hengchen Dai, Katherine L. Milkman, and Shlomo Benartzi (NBER, 2016).“The Fresh Start Effect: Temporal Landmarks Motivate Aspirational Behavior,” by Hengchen Dai, Katherine L. Milkman, and Jason Riis (Management Science, 2014).“Holding the Hunger Games Hostage at the Gym: An Evaluation of Temptation Bundling,” by Katherine L. Milkman, Julia A. Minson, and Kevin G. M. Volpp (Management Science, 2013).“The Resolution Solution: Longitudinal Examination of New Year’s Change Attempts,” by John C. Norcross and Dominic J.Vangarelli (Journal of Substance Abuse, 1989). EXTRAS:How to Change: The Science of Getting from Where You Are to Where You Want to Be, by Katy Milkman (2021). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
The start of a new year is a natural moment to set goals for ourselves. But doing so can also be a little daunting. Today, we kick off a series designed to help you understand and grapple with the mental obstacles that can keep you from charting a new path. We talk with psychologist Greg Walton, who studies how our minds get trapped in negative thought spirals — and how we can begin to break free. Then, in the latest installment of our segment "Your Questions Answered," psychologist and neuroscientist Abigail Marsh answers listener questions about the minds of extremely kind and generous people.If you enjoyed our conversation with Greg Walton, don't miss our companion conversation about the emotional tools we can use to help someone who's spiraling. You can listen to that episode with a free seven-day trial to our podcast subscription, Hidden Brain+. To sign up, go to support.hiddenbrain.org. Or if you're using an Apple device, you can go to apple.co/hiddenbrain. Thanks, and Happy New Year!Episode illustration by Getty Images for Unsplash+ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
2025 gave Canada no shortage of news — political shocks, global conflict, cultural moments, and a year that pulled emotions in every direction.In Cross Country Checkup’s annual Year in News Special, guest host David Common sits down with a panel of CBC journalists: Paul Hunter, Susan Ormiston, and Aaron Wherry, reflecting on the biggest stories, the missed ones, and the conversations Canadians carried through it all.Our question: What was the most important news story of 2025? Which one didn’t get enough attention?
As she -- and her friends — approached the age of 35, senior correspondent Molly Webster kept hearing a phrase over and over: “fertility cliff.” It was a short-hand term to describe what she was told would happen to her fertility after she turned 35 — that is, it would drop off. Suddenly, sharply, dramatically. And this was well before she was supposed to hit menopause. Intrigued, Molly decided to look into it — what was the truth behind this so-called cliff, and when, if so, would she topple? This story first premiered in “Thirty Something,” a 2018 Radiolab live show that was part of, Gonads, (https://radiolab.org/series/radiolab-presents-gonads)a six-episode audio and live event series all about reproduction and the parts of us that make more of us. The live event was produced by Rachael Cusick and edited by Pat Walters.Special thanks to epidemiologist Lauren Wise, at Boston University. Plus, Emily, Chloe, and Bianca. And of course, Jad Abumrad.If you’re more of a visual person, here are the graphs we explain in the episode, we also include links to the corresponding papers in our Episode Citations Section, below!LINK TO GRAPHS:https://internal.wnyc.org/admin/cms/image/249243/EPISODE CREDITS: Reported by - Molly WebsterProduced by - Arianne WackFact-checking by - Diane A. KellyEPISODE CITATIONS:Audio:Gonads (https://radiolab.org/series/radiolab-presents-gonads/)A six-part audio series on reproduction and the parts of us that make more of usThe Menopause Mystery (https://radiolab.org/podcast/the-menopause-mystery)One of Radiolab’s most listened-to episodes of 2025! Videos:“Radiolab Presents: Thirty Something”https://youtu.be/LOJVAaSwags?si=czCBraHf1JEqmAQiResearch Articles:Graph 1: Can assisted reproduction technology compensate for the natural decline in fertility with age? A model assessment (https://zpr.io/ft6dqdbkJnTd) Graph 2: Ovarian aging: mechanisms and clinical consequences (https://zpr.io/GrPLebynpvxV) , Brookmans, et al.BUT, the graph was borrowed and actually comes from this 1991 paper, Delaying childbearing: effect of age on fecundity and outcome of pregnancy” (https://zpr.io/whWg2UAZsb6h) Graph 3 and 4: Age and fecundability in a North American preconception cohort study, (https://zpr.io/Rmqry4Kd67hY) Wise et al; Dutch fertility researchFurther reading: Predicting Fertility, (https://zpr.io/YEdfiYT29rUh): Magazine article on Lauren Wise’s research, Sign up for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Signup (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
